120+ Organic Acids Profile, Urine
Orderable by Ontario ND
Test
Clinical Utility
The US BioTek 120 Organic Acids Profile is a urine-based metabolic assessment that measures 120 organic acid metabolites associated with carbohydrate metabolism, fatty acid oxidation, citric acid cycle activity, amino acid and B-vitamin metabolism, neurotransmitter metabolism, oxidative stress, detoxification pathways, microbial metabolites, and nutritional markers. The test may provide adjunctive information regarding nutrient utilization, metabolic function, microbial metabolite patterns, and biochemical imbalances when interpreted alongside clinical history, symptoms, diet, medication use, and standard clinical evaluation.
Method
Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
Result Included
- 2-Hydroxybutyric Acid
- 2-Hydroxyglutaric Acid
- 2-Hydroxyisocaproic Acid
- 2-Hydroxyisovaleric Acid
- 2-Ketoisocaproic Acid
- 2-Ketoisovaleric Acid
- 2-Oxo-4-methylbutyric Acid (KMBA)
- 2-Oxoisocaproic Acid
- 2-Oxoisovaleric Acid
- 2-Phenylacetamide + Phenylglyoxylic Acid
- 2-Methylglutaric Acid
- 2-Methylhippuric Acid
- 3-(3-Hydroxyphenyl)-3-hydroxypropionic Acid (HPHPA)
- 3,4-Dihydroxybenzoic Acid (3,4-DHBA)
- 3,4-Dihydroxyphenylacetic Acid (3-HPAA)
- 3,4-Dihydroxyphenylacetic Acid (DOPAC)
- 3-Hydroxy-3-methylglutaric Acid
- 3-Hydroxybutyric Acid
- 3-Hydroxyglutaric Acid
- 3-Hydroxyisobutyric Acid
- 3-Hydroxyisovaleric Acid
- 3-Hydroxykynurenine
- 4-Hydroxybenzoic Acid (4-HBA)
- 4-Hydroxyhippuric Acid
- 4-Hydroxyphenylacetic Acid (4-HPAA)
- 4-Hydroxyphenyllactic Acid (4-HPLA)
- 5-Hydroxyindoleacetic Acid (5-HIAA)
- 5-Hydroxymethyl-2-furoic Acid
- Acetoacetic Acid
- Acetylglycine
- Adipic Acid
- Alpha-Ketoglutaric Acid
- Arabinose
- Ascorbic Acid (Vitamin C)
- Azelaic Acid
- Benzoic Acid
- Beta-Hydroxybutyric Acid
- Cis-Aconitic Acid
- Citramalic Acid
- Citric Acid
- Creatinine, Urine
- D-Arabinitol
- Ethylmalonic Acid
- FIGLU (Formiminoglutamic Acid)
- Fumaric Acid
- Furan-2,5-dicarboxylic Acid
- Glucaric Acid
- Glucose (OA)
- Glyceric Acid
- Glycolic Acid
- Guanidinoacetic Acid (GAA)
- Guinolinic Acid
- Hippuric Acid
- Hexanoylglycine
- Homovanillic Acid (HVA)
- HVA/VMA Ratio
- Indoleacetic Acid (IAA)
- Isobutyrylglycine
- Isocitric Acid
- Kynurenic Acid
- Kynurenic/Quinolinic Ratio
- Lactic Acid
- Leukotriene E4
- Malic Acid
- Malonic Acid
- Mandelic Acid
- Methylcitric Acid
- Methylmalonic Acid (MMA)
- Methylsuccinic Acid
- Monosethyl Phthalate
- N-Acetylaspartic Acid
- N-Acetylcysteine (NAC)
- N-Acetylphenylalanine
- N-Acetyltyrosine
- N-Butyrylglycine
- N-Valerylglycine
- Orotic Acid
- Oxalic Acid
- Phenylacetic Acid
- Phenylglyoxylic Acid
- Phenylpyruvic Acid (PPA)
- Picolinic Acid
- Pimelic Acid
- Propionylglycine
- Pyroglutamic Acid
- Pyruvic Acid
- Quinolinic Acid
- Quinolinic Acid/5-HIAA Ratio
- Sebacic Acid
- Suberic Acid
- Succinic Acid
- Tartaric Acid
- Thymine
- Tricarballylic Acid
- Uracil
- Vanillylmandelic Acid (VMA)
- Xanthurenic Acid
Aliases/Synonyms
OAT, Organic Acids
Test Location
US BioTek
Specimen
Specimen Type
Urine
Containers
Collection Containers
Urine container
Volume
Sample Volume
5 mL
Minimum Volume
5 mL
Collection & Handling
Collection Instructions
Patients are instructed to collect a first morning urine sample before eating or drinking, or the first urine after the longest period of sleep. Collection should not be performed during menstruation, while experiencing a urinary tract infection, or while taking methylene blue. Excessive fluid intake should be avoided the evening before collection to prevent sample dilution. The sample is collected mid-stream into the provided collection container, labeled with patient information, and shipped to the laboratory within 48 hours of collection.
Additional Information
ICL Integrative Laboratory Services Clients: A specimen collection kit is available for registered ILS Clients with active accounts – you may login and order kits online here. Or you may register for an ILS Account here.
Stability
| Ambient |
|---|
| 10 days |
Rejection Criteria
| Criteria | Specification |
|---|---|
| Specimen | During menstration |
| Specimen | Experiencing a urinary tract infection |
| Specimen | While taking methylene blue |
Sample Report
Turnaround Time
21 days