Test
Clinical Utility
The Diagnostic Solutions Laboratory OAp™ Organic Acids Profile is a urine-based metabolomic assessment that evaluates organic acid metabolites associated with energy production, mitochondrial function, fatty acid oxidation, neurotransmitter metabolism, nutritional status, oxidative stress, detoxification pathways, microbial metabolites, and metabolic function. The test may provide adjunctive information related to biochemical pathway activity, nutrient utilization, gut microbial metabolite patterns, and metabolic imbalances when interpreted alongside clinical history, symptoms, diet, medication use, and standard clinical evaluation.
Result Included
- Pyruvic Acid
- Lactic Acid
- D-Lactic Acid
- Citric Acid
- Cis-Aconitic Acid
- Isocitric Acid
- Alpha-Ketoglutaric Acid
- Succinic Acid
- Fumaric Acid
- Malic Acid
- Adipic Acid
- Suberic Acid
- Sebacic Acid
- Ethylmalonic Acid
- Methylsuccinic Acid
- Pimelic Acid
- Glutaric Acid
- 3-Hydroxybutyric Acid
- 2-Hydroxybutyric Acid
- Alpha-Ketobutyric Acid
- Alpha-Ketoisovaleric Acid
- Alpha-Ketoisocaproic Acid
- Alpha-Keto-Beta-Methylvaleric Acid
- Total Branched-Chain Keto Organic Acids
- Hexanoylglycine
- Suberylglycine
- 3-Hydroxyisovaleric Acid
- Methylmalonic Acid
- Formiminoglutamic Acid (FIGLU)
- Xanthurenic Acid
- Hydroxykynurenine
- Pyridoxic Acid
- Orotic Acid
- Quinolinic Acid
- Kynurenic Acid
- Picolinic Acid
- Homovanillic Acid (HVA)
- Vanillylmandelic Acid (VMA)
- 5-Hydroxyindoleacetic Acid (5-HIAA)
- HVA/VMA Ratio
- Quinolinic/Kynurenic Ratio
- Cortisol
- Cortisone
- Cortisol/Cortisone Ratio
- Aldosterone
- Pyroglutamic Acid
- 8-Hydroxy-2-Deoxyguanosine
- Glucaric Acid
- Mandelic Acid
- 2-Methylhippuric Acid
- Benzoic Acid
- Hippuric Acid
- Phenylacetic Acid
- 3-Phenylpropionylglycine
- 4-Hydroxyphenylacetic Acid
- 4-Hydroxyphenylpyruvic Acid
- 4-Hydroxybenzoic Acid
- 3-Indoleacetic Acid
- Equol
- Arabinitol
- Citramalic Acid
- Tartaric Acid
- Tricarballylic Acid
- Oxalic Acid
- Glyceric Acid
- Glycolic Acid
- Homogentisic Acid
- Benzoylformic Acid
- Quercetin
- Glucose
- Fructose
- Albumin
- Microalbumin
- Creatinine
- Phosphate.
Test Location
Diagnostic Solutions Laboratory
Specimen
Specimen Type
Urine
Volume
Minimum Volume
15 mL
Specimen Comment
Freeze sample prior to shipping
Collection & Handling
Collection Instructions
The OAp™ Organic Acids Profile uses a first-morning urine specimen collected at home using the kit provided by the laboratory. Patients are instructed to empty the bladder before bedtime and discard that urine, then collect the first morning urine after a minimum six-hour hold. Fruits, jams, and jellies should be avoided for 48 hours prior to collection, and prescription medications should not be discontinued unless directed by a healthcare provider. The urine is collected directly into the provided specimen cup, ensuring a minimum of 15 mL and no more than 50 mL. The sample container must be securely closed, placed into the provided specimen bag with the completed requisition form, and frozen for a minimum of two hours prior to shipment. If shipping is delayed, the specimen should remain frozen until shipment.
Additional Information
ICL Integrative Laboratory Services Clients: A specimen collection kit is available for registered ILS Clients with active accounts – you may login and order kits online here. Or you may register for an ILS Account here.
Stability
| Frozen |
|---|
| 7 days |
Rejection Criteria
| Criteria | Specification |
|---|---|
| Specimen | Leaking from container or not properly sealed |
| Specimen | Insufficient volume |
| Specimen | Not frozen prior to shipping |
Sample Report
Turnaround Time
10 days